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https://repositorio-socioecologia.conahcyt.mx/jspui/handle/1000/340| Participation of IL-6 in chronic kidney disease | |
| Rosa Cremades González | |
| Acceso Abierto | |
| Atribución | |
| Chronic kidney disease (CKD) is a kidney condition whereby the structure and function of the kidneys is damaged and compromised for a minimum of three months. The global prevalence of CKD in the general population in 2017 was estimated at 9.1%, which represents approximately 700 million cases. In Mexico, kidney failure related to diabetes mellitus represents 25% of deaths due to diabetes, while kidney failure related to arterial hypertension represents 28% of deaths related to in-tensive heart disease, and non-specific kidney failure represents 6% of deaths classified as nephritis and nephrosis. CKD is a disease mainly driven by an inflammatory process and in more advanced stages, by fibrosis. These processes go hand in hand with the expression of multiple proinflammatory cytokines, including IL-6. lt is widely reported that elevated levels of IL-6 correspond to the progression of CKD, due to its secretion stimulated by oxidative stress and pro-inflammatory factors or accumulation due to decreased renal capacity. The present review aims to know the IL-6 effects on the inflammation in chronic kidney disease process. | |
| Colegio Mexicano de Urología | |
| 2024 | |
| Artículo | |
| Español | |
| Estudiantes Investigadores Otros | |
| MEDICINA Y CIENCIAS DE LA SALUD | |
| Versión publicada | |
| publishedVersion - Versión publicada | |
| Appears in Collections: | Documentos |
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